Metabolic syndrome and its components in men
Herman Adriansjah1, John M F Adam
1Diabetes and Lipid center, Division of Metabolic and Endocrinology, Department of Internal Medicine, Medical Faculty, Hasanudin University, dr. Wahidin Sudirohusodo Hospital, Makassar.
Acta Medica Indonesiana
|January 14, 2010
Summary
Metabolic syndrome is common in apparently healthy men, particularly those with large waist circumference (WC). A WC of 90 cm or greater can serve as an effective screening tool for identifying metabolic syndrome in men.
Area of Science:
- Cardiology
- Endocrinology
- Public Health
Background:
- Metabolic syndrome is a cluster of conditions that increase the risk of heart disease, stroke, and type 2 diabetes.
- Prevalence and risk factors for metabolic syndrome in men require further investigation.
Purpose of the Study:
- To determine the prevalence of metabolic syndrome and its components in apparently healthy men.
- To evaluate the utility of waist circumference as a screening tool for metabolic syndrome.
Main Methods:
- A cross-sectional study was conducted on 227 apparently healthy men undergoing routine medical examinations.
- Metabolic syndrome was diagnosed using modified National Cholesterol Education Program Adult Treatment Panel III (NCEP ATP III) criteria, including waist circumference (≥90 cm for Asian men), blood pressure, triglycerides, HDL-cholesterol, and glucose intolerance.
- Physical examinations and laboratory tests were performed after a 12-hour fast.
Main Results:
- 127 out of 227 men (56.4%) met the criteria for metabolic syndrome.
- A significantly higher prevalence of metabolic syndrome was observed in men with a waist circumference ≥90 cm (79.2%) compared to those with <90 cm (relative risk 11.3).
- Reducing the waist circumference threshold to ≥85 cm identified 66.5% of subjects with metabolic syndrome.
Conclusions:
- Metabolic syndrome is prevalent in apparently healthy men, with a strong association with increased waist circumference.
- Waist circumference ≥90 cm is a reliable and practical screening tool for detecting metabolic syndrome in men.
- Early identification and management of metabolic syndrome risk factors are crucial for preventing cardiovascular disease and diabetes.
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