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Updated: Jun 17, 2026
Learning Modern Laryngeal Surgery in a Dissection Laboratory
Published on: March 18, 2020
[Prognostic factors and comorbidity impact upon the frontolateral laryngectomy]
Rogério Aparecido Dedivitis1, Jozías de Andrade-Sobrinho, Mario Augusto Ferrari de Castro
1Livre Docente pela Fundação Lusíada, Santos, SP-BR. dedivitis.hns@uol.com.br
Objective:
To evaluate the survival rates, comorbidity impact, complications, and treatment failure facts.
Methods:
38 patients clinically staged as T1b / T2N0M0 glottic tumors were analyzed. They underwent frontolateral laryngectomy with reconstruction, from January, 1995 to December, 2006. The oncological outcome, comorbidity (through the Adult Comorbidity Evaluation -27 ACE-27 scale) and complications were studied and correlated to the demographic data and tumor characteristics.
Results:
Eight patients presented local recurrence being surgically salvaged. Complications were not observed in 33 patients. There was no significant difference on the global and free of disease 5-year survival regarding the diverse comorbidity categories. Only the pathological margins spread of the tumor presented significant difference on the global (p=0.0033) and free of disease survival (p<0.0001).
Conclusion:
The 5-year global survival was 67.6% whereas the free of disease survival was 73.7%; the comorbidity did not represent independent prognostic factor; the postoperative complications rate was 13.2%; and only the pathological margin spread showed significant difference on the global and free of disease survival rates.
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