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Drug dependence, abuse, and addiction are complex phenomena that can precipitate various abnormal states. Physical dependence refers to a state of pharmacological adaptation to a drug. This adaptation often results in tolerance—a reduced response to the drug after repeated administrations. When the drug use is abruptly stopped, withdrawal symptoms occur due to the body's need to readjust from the pharmacologically induced imbalance. However, tolerance and withdrawal symptoms do not necessarily...
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A General Method for Evaluating Deep Brain Stimulation Effects on Intravenous Methamphetamine Self-Administration
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Published on: January 22, 2016

The methamphetamine problem in the United States.

Rachel Gonzales1, Larissa Mooney, Richard A Rawson

  • 1Integrated Substance Abuse Programs, Semel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine, University of California, Los Angeles, California 90025, USA. rachelmg@ucla.edu

Annual Review of Public Health
|January 15, 2010
PubMed
Summary
This summary is machine-generated.

Methamphetamine (MA) use presents a significant public health challenge in the US, despite conflicting data. This review examines MA trends, at-risk groups, and interventions to address this complex issue.

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Area of Science:

  • Public Health
  • Epidemiology
  • Substance Abuse Research

Background:

  • Methamphetamine (MA) production and use have escalated over 25 years, creating significant public health issues in the US.
  • Controversy exists regarding the scale of the MA problem, with conflicting data from national surveys versus law enforcement and treatment admissions.

Purpose of the Study:

  • To provide a comprehensive overview of the methamphetamine (MA) problem in the United States.
  • To analyze historical context, epidemiological trends, at-risk populations, associated health and social factors, and interventions for MA use.

Main Methods:

  • Review of diverse data sources, including national surveys, law enforcement data, welfare agencies, substance abuse treatment admissions, criminal justice data, and executive reports.
  • Analysis of historical underpinnings and epidemiological trends in MA use.
  • Identification of key subgroups, risk factors, and health/social correlates of MA problems.

Main Results:

  • National surveys suggest MA use is a minor concern, contrasting with data from law enforcement, treatment programs, and other agencies indicating a significant public health problem.
  • Identified key subgroups at risk, health and social factors associated with MA use, and reviewed available interventions.
  • Examined lessons learned from past efforts to address MA-related issues.

Conclusions:

  • The methamphetamine (MA) problem is substantial and multifaceted, requiring a comprehensive approach.
  • Understanding epidemiological trends, at-risk populations, and effective interventions is crucial for public health strategies.
  • Addressing the MA crisis necessitates integrating data from various sources to inform policy and practice.