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Updated: Jun 17, 2026

Multi-locus Variable-number Tandem-repeat Analysis of the Fish-pathogenic Bacterium Yersinia ruckeri by Multiplex PCR and Capillary Electrophoresis
Published on: June 17, 2019
Coexistence of multiple multilocus variable-number tandem-repeat analysis subtypes of Clostridium difficile PCR
Hannah E Tanner1, Katherine J Hardy, Peter M Hawkey
1Health Protection Agency, West Midlands Public Health Laboratory, Heart of England NHS Foundation Trust, Birmingham B9 5SS, United Kingdom. Hannah.Tanner@HeartofEngland.nhs.uk
Abstract:
We investigated whether multilocus variable-number tandem-repeat analysis (MLVA) typing could identify different subtypes of Clostridium difficile ribotype 027 within the same feces specimen. Five of 39 specimens yielded at least one isolate with an MLVA profile different (more than five summed tandem repeat differences) from that of other isolates in the same specimen, thereby potentially obscuring epidemiological links between C. difficile infection cases.

