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Updated: Jun 17, 2026

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery

Published on: July 5, 2021

Intradural suprasellar chondroid chordoma.

Liu Jiagang¹, Liu Yanhui, Su Xueying

¹Department of Neurosurgery, West China Hospital, Sichuan University, Chengdu wai nan guo xue xiang 37#, Chengdu, Sichuan 610041, China.

Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia

|January 16, 2010

Summary

This study details a rare case of an entirely intradural chondroid chordoma in the suprasellar region of a 51-year-old man. The tumor was successfully removed, offering insights into this unusual brain tumor presentation.

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Area of Science:

Neurosurgery
Neuropathology
Oncology

Background:

Chordomas are rare bone tumors that typically arise at the skull base or spine.
Chondroid chordomas are a subtype characterized by chondroid elements, often associated with bone or dura.
Suprasellar tumors can present with visual disturbances and headaches due to mass effect.

Observation:

A 51-year-old male presented with headache and progressive vision loss.
Magnetic resonance imaging (MRI) revealed an isointense, heterogeneously enhancing intradural suprasellar mass.
The tumor showed no apparent bony or dural attachment.

Findings:

Gross-total resection of the suprasellar mass was achieved via a left extended pterional approach.
Histopathological examination confirmed the diagnosis of chondroid chordoma, with typical chordoma cells and chondroid matrix.
This represents the first reported instance of a purely intradural chondroid chordoma in the suprasellar location.

Implications:

This case expands the understanding of chordoma's diverse presentations and locations.
Highlights the importance of considering rare intradural tumors in the differential diagnosis of suprasellar masses.
Surgical resection via an extended pterional approach can be effective for such lesions.