[Ultrasound guided core biopsy for breast lesions using 16G needle]

Area of Science:

• Oncology
• Radiology
• Pathology

Background:

• Accurate diagnosis of breast lesions is crucial for effective treatment.
• Core-needle biopsy is a standard diagnostic tool, but optimal sample size requires evaluation.

Purpose of the Study:

• To establish a standard diagnostic evaluation protocol using 16G core-needle biopsy for breast lesions.
• To determine the ideal number of biopsy fragments for accurate breast lesion diagnosis.

Main Methods:

• A prospective study involving 79 patients with BIRADS 2-5 breast lesions.
• Utilized 16G core biopsy needles, obtaining five individually labeled formalin-fixed fragments per patient.

Main Results:

• Achieved 96% conclusive diagnoses from 84 biopsies (43 malignant, 38 benign).
• Diagnostic accuracy increased with sample number, reaching 98.8% with three samples and 100% with five.
• Three fragments yielded a satisfactory diagnostic accuracy of 98.8%.

Conclusions:

• Resection of three core-needle biopsy fragments is sufficient for satisfactory diagnostic evaluation of breast lesions.
• This standardized approach improves diagnostic yield and accuracy in breast lesion assessment.