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Fecal Microbiota Transplantation via Colonoscopy for Recurrent C. difficile Infection
Published on: December 8, 2014
Prevalence of diverticulosis in recurrent Clostridium difficile infection
Michael J Lipp1, Odelya E Pagovich, David Rabin
1Division of Digestive Diseases, Beth Israel Medical Center, New York, NY 10003, United States. mlipp@chpnet.org
Aim:
To re-evaluate the theory that colonic diverticulosis is associated with relapse of Clostridium difficile associated disease (CDAD) in light of data suggesting increasing rates of CDAD infection and relapse.
Methods:
Charts were reviewed for patients with recurrent CDAD who had also had a prior colonoscopy or flexible sigmoidoscopy. An age and gender matched control group was used to compare the prevalence of diverticulosis.
Results:
Twenty-two patients met the study criteria, and the prevalence of diverticulosis in patients with CDAD relapse was 23% compared to 32% in age and sex matched controls (P = 0.44). A significant proportion of patients with CDAD relapse had co-morbidities associated with immune suppression.
Conclusion:
Diverticulosis does not appear to be associated with CDAD relapse.
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