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Single-Molecule Fluorescence Visualization of DNA Polymerase Dynamics at G-Quadruplexes
Published on: April 4, 2025
High fluorescence selectivity and visual detection of G-quadruplex structures by a novel dinuclear ruthenium complex
Liang Xu1, Dan Zhang, Jing Huang
1College of Chemistry and Molecular Sciences, Key Laboratory of Biomedical Polymers of Ministry of Education, State Key Laboratory of Virology, Wuhan University, Hubei, Wuhan, 430072, P. R. China.
Chemical Communications (Cambridge, England)
|January 21, 2010
Abstract:
A novel dinuclear ruthenium(II) complex with high fluorescent selectivity between DNA quadruplex structures and duplex structures was generated, and using an iodide-quenching strategy, G-quadruplex structures can be easily distinguished from duplex structures by the naked eye.
