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Related Concept Videos

Immunodeficiency Diseases01:25

Immunodeficiency Diseases

Immunodeficiency disorders are conditions in which the immune system's ability to fight infectious disease and cancer is compromised or entirely absent. The immune system comprises a complex network of cells, tissues, and organs that work together to protect the body from potentially harmful invaders. When this system is deficient or not functioning properly, it leaves the body susceptible to infections, diseases, or other complications.
There are three main causes of immunodeficiency disorders...
Vitamins01:30

Vitamins

Vitamins, derived from the Latin word for life, are essential organic substances required in small quantities for optimal growth and overall well-being. Unlike other organic nutrients, vitamins don't act as sources of energy or building materials but rather facilitate these nutrients' utilization by the body. Vitamins are predominantly coenzymes, assisting enzymes in specific chemical actions, like the oxidation of glucose for energy involving B vitamins. Most vitamins are not produced in our...
Inborn Errors of Metabolism01:20

Inborn Errors of Metabolism

Phenylketonuria (PKU) is a protein metabolism disorder characterized by high blood levels of the amino acid phenylalanine. This results from a mutation in the gene responsible for phenylalanine hydroxylase, an enzyme that converts phenylalanine into tyrosine. When this enzyme is deficient, phenylalanine builds up in the blood, leading to symptoms such as vomiting, rashes, seizures, growth deficiency, and severe mental retardation. An early diagnosis and a diet restricting phenylalanine intake...
Disorders of Erythrocytes01:27

Disorders of Erythrocytes

Disorders of erythrocytes, or red blood cells (RBCs), include a range of conditions affecting their number, shape, or function.
Erythrocyte disorders can be broadly categorized into two main types: anemic and polycythemic conditions.
A low oxygen-carrying capacity of the blood due to the loss, lower production, or destruction of erythrocytes is termed anemia. Hemorrhagic anemia, for example, occurs when bleeding from an external wound or internal ulcer reduces erythrocyte counts.
On the other...
Graves Disease II: Pathophysiology01:24

Graves Disease II: Pathophysiology

Graves’ disease is an autoimmune disorder characterized by the production of thyroid-stimulating immunoglobulins (TSI) that activate TSH receptors, leading to excessive synthesis and release of thyroid hormones (T3 and T4) and resulting in hyperthyroidism.Among all causes of hyperthyroidism, Graves’ disease is the most common and can happen at any age, though it is more frequent in women. It produces a hypermetabolic state with features such as weight loss, tachycardia, tremor, and heat...
Incomplete Dominance01:43

Incomplete Dominance

Gregor Mendel's work (1822 - 1884) was primarily focused on pea plants. Through his initial experiments, he determined that every gene in a diploid cell has two variants called alleles inherited from each parent. He suggested that amongst these two alleles, one allele is dominant in character and the other recessive. The combination of alleles determines the phenotype of a gene in an organism.

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Articles linked to this work by shared authors, journal, and citation graph.

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[Consensus of Mexican experts on long-term prophylaxis in patients with hereditary angioedema in Mexico].

Revista alergia Mexico (Tecamachalco, Puebla, Mexico : 1993)·2026
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Pediatric asthma treatment: What to do when international guideline recommendations do not agree.

Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology·2018
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Correction: A Multicenter, Open-Label, Controlled Phase II Study to Evaluate Safety and Immunogenicity of MVA Smallpox Vaccine (IMVAMUNE) in 18-40 Year Old Subjects with Diagnosed Atopic Dermatitis.

PloS one·2015
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A Multicenter, Open-Label, Controlled Phase II Study to Evaluate Safety and Immunogenicity of MVA Smallpox Vaccine (IMVAMUNE) in 18-40 Year Old Subjects with Diagnosed Atopic Dermatitis.

PloS one·2015
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Transfer factor and allergy.

Revista alergia Mexico (Tecamachalco, Puebla, Mexico : 1993)·2011
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[Association between chronic urticaria and Helicobacter pylori].

Revista alergia Mexico (Tecamachalco, Puebla, Mexico : 1993)·2008

Related Experiment Video

Updated: Jun 16, 2026

Atomic Absorbance Spectroscopy to Measure Intracellular Zinc Pools in Mammalian Cells
13:04

Atomic Absorbance Spectroscopy to Measure Intracellular Zinc Pools in Mammalian Cells

Published on: May 16, 2019

[IgE deficiency: a forgotten disease?].

Susana García Pavón Osorio1, José Jesús López Tiro, Javier Gómez Vera

  • 1Servicio de Alergia e Inmunología, quinto piso, Hospital Regional Lic. Adolfo López Mateos. Universidad 1321, colonia Florida, 01030 México, DF. sus_gar_pav@yahoo.com.mx

Revista Alergia Mexico (Tecamachalco, Puebla, Mexico : 1993)
|January 22, 2010
PubMed
Summary

Selective IgE deficiency, characterized by very low serum IgE levels, can present with recurrent respiratory infections. Further clinical studies are needed for precise diagnosis and understanding of this condition.

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Area of Science:

  • Immunology
  • Allergy and Clinical Immunology

Context:

  • Selective IgE deficiency is a rare condition defined by serum IgE levels below 5 UI/mL.
  • While often asymptomatic, it can be linked to recurrent respiratory infections, fatigue, and musculoskeletal issues.

Purpose:

  • To describe the clinical evolution and treatment outcomes in patients diagnosed with selective IgE deficiency.
  • To analyze patient data including atopy history, concurrent diseases, allergic manifestations, and treatment responses.

Summary:

  • Eleven patients (5 female, 6 male; ages 16 months to 10 years) with serum IgE < 5 UI/mL and normal immunoglobulin levels (except one with IgA deficiency) were studied.
  • Treatments ranged from prophylactic antibiotics to intravenous immunoglobulin therapy.
  • Diagnosis was established based on low serum IgE and recurrent respiratory infections.

Impact:

  • Highlights the association between low serum IgE and recurrent respiratory infections, aiding in diagnostic criteria.
  • Underscores the need for more extensive clinical research to precisely define and manage selective IgE deficiency.
  • Provides insights into treatment approaches for this rare immunodeficiency.