Related Experiment Video
Updated: Jun 16, 2026

Rodent Inferior Vena Cava Venoplasty Balloon Model
Published on: May 24, 2024
[Pain and other symptoms of chronic venous diseases: pathophysiology and therapeutic principles]
Abstract:
The literature review presented herein analyses the mechanism of the development of pain and othersubjective signs and symptoms in chronic venous diseases. Also discussed are numerous findings suggesting a pivotal role played by the leukocytic-endothelial inflammatory reaction as the main stimulator of the nociceptors of the venous wall and paravasal tissue, resulting information of the pain syndrome. This is followed by substantiating the necessity of early initiation of comprehensive conservative therapy making it possible to block the molecular and cellular mechanisms damaging the venous wall and microcirculatory bed in patients presenting with various stages of venous chronic diseases.
Related Concept Videos
Venous Thrombosis IV: Nursing Management
Varicose Veins I: Introduction
Varicose Veins II: Diagnostic Studies and Interprofessional Care
Venous Thrombosis III: Interprofessional Care
Venous Thrombosis I: Introduction
Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies

