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Cytogenetic analysis of a congenital fibrosarcoma
L R Adam1, E V Davison, A J Malcolm
1Division of Human Genetics, University of Newcastle upon Tyne, England.
Cancer Genetics and Cytogenetics
|March 1, 1991
Abstract:
Congenital (infantile) fibrosarcoma is a rare soft tissue sarcoma occurring in children aged less than 5 years. We performed cytogenetic analysis on such a tumor, which had an abnormal karyotype: 48,XY, +11, +20. Three other reports of karyotypes in congenital fibrosarcoma describe similar cytogenetic changes, and a specific pattern of trisomies that may prove diagnostic for this tumor is beginning to emerge.