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Related Experiment Videos

Oral sedation for diagnostic upper endoscopy.

J L Hedenbro1, M Ekelund, T Aberg

  • 1Dept. of Surgery, Lund University, Sweden.

Endoscopy
|January 1, 1991
PubMed
Summary
This summary is machine-generated.

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Oral triazolam significantly reduced patient discomfort during upper GI endoscopy compared to placebo. This oral premedication allows patients to resume normal activities post-procedure, optimizing endoscopy resources.

Area of Science:

  • Gastroenterology
  • Pharmacology

Background:

  • Intravenous (i.v.) sedation in upper gastrointestinal (GI) endoscopy necessitates recovery facilities and delays patient activities.
  • The costs associated with i.v. sedation and recovery impact the efficiency of outpatient endoscopy procedures.

Purpose of the Study:

  • To evaluate the efficacy of oral premedication in reducing patient discomfort during upper GI endoscopy.
  • To determine if oral administration can mitigate the disadvantages of i.v. sedation, such as prolonged recovery.

Main Methods:

  • A randomized trial involving 400 outpatients undergoing upper GI endoscopy.
  • Patients received either oral triazolam (0.125 mg) or a placebo.
  • Patient discomfort and procedural aspects were assessed using visual analogue scale questionnaires.

Related Experiment Videos

Main Results:

  • Oral triazolam significantly reduced patient discomfort (38.6 vs 44.8 on visual analogue scale, p = 0.0379).
  • No significant differences were observed in post-endoscopy information recall or endoscopy quality between groups.
  • No patients required extended recovery or hospitalization; one reported drowsiness.

Conclusions:

  • Oral premedication with triazolam is a valuable option for upper GI endoscopy, reducing patient discomfort.
  • This approach optimizes endoscopy resource utilization and does not impede post-procedure patient activities.