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Human Fetal Blood Flow Quantification with Magnetic Resonance Imaging and Motion Compensation
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Single-voxel MRS with prospective motion correction and retrospective frequency correction
1Medical Physics, Department of Diagnostic Radiology, University Hospital of Freiburg, Freiburg, Germany. zaitsev@ukl.uni-freiburg.de
NMR in Biomedicine
|January 27, 2010
Summary
Subject motion degrades magnetic resonance spectroscopy (MRS) quality. This study shows prospective motion correction, using real-time tracking and interleaved scans, effectively suppresses motion-induced artefacts in proton MRS.
Area of Science:
- Medical Imaging
- Spectroscopy
- Biophysics
Background:
- Subject motion is a significant limitation in Magnetic Resonance Spectroscopy (MRS) investigations, reducing spectral quality and diagnostic value.
- Previous work has shown the potential of external motion tracking for correcting artifacts in Magnetic Resonance (MR) imaging.
Purpose of the Study:
- To investigate the utility of prospective motion correction (PMC) for single-voxel proton MRS.
- To assess methods for mitigating motion-induced artifacts in MRS.
Main Methods:
- Real-time use of object motion data to update the spectroscopy voxel position before each sequence repetition.
- Implementation of an interleaved reference scan method to address shim changes accompanying subject motion.
Main Results:
- Prospective motion correction effectively updated the spectroscopy voxel position in real time.
- The interleaved reference scan method successfully suppressed adverse frequency shifts caused by subject motion.
Conclusions:
- Prospective motion correction is a viable strategy for improving the quality of single-voxel proton MRS.
- Combining real-time voxel repositioning with interleaved reference scans effectively overcomes motion-related artifacts in MRS.
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