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Updated: Jun 16, 2026
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Porcine Liver Transplantation Without Veno-Venous Bypass As an Extended Criteria Donor Model
Published on: August 17, 2022
Scoring short-term mortality after liver transplantation
Chung-Shun Wong1, Wei-Chen Lee, Chang-Chyi Jenq
1Institute of Emergency and Critical Care Medicine, National Yang-Ming University, Taipei, Taiwan.
Summary
The Sequential Organ Failure Assessment (SOFA) score effectively predicts mortality after liver transplantation. SOFA scores on postoperative day 7 showed the highest accuracy in forecasting patient survival outcomes.
Area of Science:
- Hepatology
- Transplantation Surgery
- Critical Care Medicine
Background:
- Liver transplantation is a life-saving procedure for end-stage liver disease.
- Accurate prediction of post-transplant mortality is crucial for patient management.
- Existing scoring systems have limitations in predicting outcomes.
Purpose of the Study:
- To compare the predictive power of four scoring systems for post-liver transplant mortality.
- To identify the most accurate scoring system and time point for predicting outcomes.
Main Methods:
- Retrospective review of 149 liver transplant recipients from 2000-2007.
- Assessment using Child-Pugh, MELD, RIFLE, and SOFA scores pre-transplant and post-transplant (days 1, 3, 7, 14).
- Statistical analysis to evaluate discriminatory power and predictive accuracy.
Main Results:
- The overall 1-year survival rate was 77.9%.
- The SOFA score demonstrated superior discriminatory power compared to Child-Pugh, MELD, and RIFLE criteria.
- SOFA score on postoperative day 7 showed the highest accuracy for predicting 3-month and 1-year mortality.
Conclusions:
- SOFA scores are significant predictors of 3-month and 1-year mortality after liver transplantation.
- SOFA score on postoperative day 7 offers the best discriminative power for predicting mortality.
- This finding can aid in optimizing patient care and resource allocation post-transplant.
