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Targeted Microinjection and Electroporation of Primate Cerebral Organoids for Genetic Modification
Published on: March 24, 2023
Depolarising primate experimentation: the good, the bad and the determined
1FRAME, Russell & Burch House, 96-98 North Sherwood Street, Nottingham NG1 4EE, UK. michelle@frame.org.uk
Alternatives to Laboratory Animals : ATLA
|January 29, 2010
Summary
This research explores the ethical considerations and scientific feasibility of replacing primate research. It aims to foster dialogue and find constructive solutions for animal welfare in scientific advancement.
Area of Science:
- Animal research ethics
- Biomedical science
- Alternatives to animal testing
Background:
- The Three Rs (Replacement, Reduction, Refinement) are crucial for ethical laboratory animal use.
- FRAME actively promotes and advances the Three Rs in scientific research.
- Primate research presents a significant ethical and scientific dilemma.
Purpose of the Study:
- To examine scientists' perspectives on the opportunities and challenges of primate use in biomedical research.
- To investigate the feasibility of phasing out primate use in scientific studies.
- To contribute a new perspective to depolarize the debate surrounding primate research.
Main Methods:
- Multidisciplinary PhD project focusing on primate use in biomedical research.
- Qualitative examination of research scientists' views.
- Analysis of opportunities, challenges, and feasibility of replacing primate experiments.
Main Results:
- Personal experiences highlight optimism, frustration, and determination in advocating for alternatives.
- The primate research dilemma serves as a key illustration of these experiences.
- The research aims to gather data on scientists' views to inform future strategies.
Conclusions:
- Phasing out primate research requires a constructive dialogue between all stakeholders.
- Providing new perspectives can help depolarize the debate on primate use.
- The ultimate goal is to advance scientific research while improving animal welfare.

