[Spatial-temporal organization of mitochondria in nerve cells during rest and excitation]

Spatial reorganization of mitochondria in the nerve cell reflects, at the microstructural level, the control of its respiration and oxidative metabolism. During the first two minutes of excitation no changes are observed in the degree of mitochondrion aggregation, while cytochrome oxidase activity in them sharply increases. When the frequency of pulse activity stabilizes, mitochondria aggregate, cytochrome oxidase activity decreases, mainly in the aggregated mitochondria.