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Published on: June 10, 2025
Early deaths in patients with heart failure discharged from the emergency department: a population-based analysis
Douglas S Lee1, Michael J Schull, David A Alter
1Division of Cardiology, Institute for Clinical Evaluative Sciences, Toronto General Hospital, Toronto, Ontario, Canada. dlee@ices.on.ca
Insights
Patients with heart failure (HF) discharged from the emergency department (ED) face significant early death risks. These risks, particularly for those with comorbidities, can be higher than for admitted patients.
Area of Science:
- Cardiology
- Emergency Medicine
- Public Health
Background:
- Approximately one-third of patients presenting to the emergency department (ED) with heart failure (HF) are discharged home.
- Little is known about the subsequent care and outcomes for these patients.
Purpose of the Study:
- To examine the acute care and early outcomes of patients with HF discharged from the ED without hospital admission.
- To identify risk factors for 30-day mortality in this patient group.
Main Methods:
- Retrospective cohort study of 50,816 patients with HF visiting an ED in Ontario, Canada (April 2004 - March 2007).
- Analysis of factors influencing discharge decisions and 30-day and 90-day mortality.
- Comparison of mortality rates between discharged and admitted patients with similar predicted risks.
Main Results:
- 31.7% of HF patients (16,094/50,816) were discharged from the ED.
- 4.0% died within 30 days of ED admission; 1.3% died within 7 days of ED discharge.
- Multiple previous HF admissions, valvular heart disease, peripheral vascular disease, and respiratory disease increased 30-day death risk (ORs 1.33-1.64).
- Older age, ambulance arrival, higher triage acuity, and ED resuscitation increased likelihood of admission.
- Discharged patients with comparable predicted risks had higher 90-day mortality (11.9%) than admitted patients (9.5%).
Conclusions:
- Patients with HF discharged from the ED face substantial early mortality risks.
- These risks may exceed those of hospitalized HF patients.
- Risk stratification and appropriate follow-up are crucial for discharged HF patients.
Background:
Although approximately one third of patients with heart failure (HF) visiting the emergency department (ED) are discharged home, little is known about their care and outcomes.
Methods And Results:
We examined the acute care and early outcomes of patients with HF who visited an ED and were discharged without hospital admission in Ontario, Canada, from April 2004 to March 2007. Among 50 816 patients (age, 76.4+/-11.6 years; 49.4% men) visiting an ED for HF, 16 094 (31.7%) were discharged without hospital admission. A total of 4.0% died within 30 days from admission, and 1.3% died within 7 days of discharge from the ED. Although multiple (>or=2) previous HF admissions (odds ratio [OR], 1.64; 95% CI, 1.14 to 2.31), valvular heart disease (OR, 1.37; 95% CI, 1.00 to 1.84), peripheral vascular disease (OR, 1.41; 95% CI, 1.00 to 1.93), and respiratory disease (OR, 1.33; 95% CI, 1.08 to 1.63) increased the risk of 30-day death among those discharged from the ED, presence of these conditions did not increase the likelihood of admission. Patients were more likely to be admitted if they were older (OR, 1.08; 95% CI, 1.06 to 1.10 per decade), arrived by ambulance (OR, 2.02; 95% CI, 1.93 to 2.12), had a higher triage acuity score (OR, 4.12; 95% CI, 3.84 to 4.42), or received resuscitation in the ED (OR, 2.85; 95% CI, 2.68 to 3.04). In those with comparable predicted risks of death, subsequent 90-day mortality rates were higher among discharged than admitted patients (11.9% versus 9.5%; log-rank P=0.016).
Conclusions:
Patients with HF who are discharged from the ED have substantial risks of early death, which, in some cases, may exceed that of hospitalized patients.
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