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Evaluating Statin Knowledge-Perceptions and Receptivity Following a Comprehensive Lifestyle Modification Program
Alaina Pupulin1, Jillian Ball1, Ravi Bajaj1
1Faculty of Medicine, University of Ottawa, Ottawa, ON, Canada (AP); Faculty of Art and Science, University of Toronto, Toronto, ON, Canada (JB); Faculty of Medicine, University of Toronto, Toronto, ON, Canada (RB, DAA); Institute of Health Policy, Management, and Evaluation, University of Toronto, Toronto, ON, Canada (DAA); Rehabilitation Institute-University Health Network, University of Toronto, Toronto, ON, Canada (DAA); Institute for Clinical Evaluative Sciences, Toronto, ON, Canada (DAA).
Background:
Though clinical guidelines for cholesterol-lowering therapies advocate for both a trial of lifestyle modification and the initiation of statin medication when appropriate, the extent to which lifestyle modification may alter a patient's knowledge-perceptions and receptivity towards statins remains unclear.
Methods:
Following completion of a 6-month comprehensive lifestyle modification program, perceived changes in knowledge and receptivity towards statins were examined across prespecified subgroups of age, sex, and statin eligibility using a mixed-methods questionnaire. Quantitative and qualitative analyses incorporated binomial tests, McNemar's test, and thematic analyses.
Results:
Among 192 patients who completed the program and exit questionnaire between December 15, 2020 and July 2, 2021, 88.4% of patients indicated a perceived improvement in cholesterol and/or statin knowledge (P < .0001). 48.2% of patients acknowledged that their receptivity towards taking statins increased (P = .61). Changes in receptivity were attributed to several identified program themes including improvements in health knowledge and awareness, motivation and empowerment. Patients who noted improvements in their mental health also reported significantly increased receptivity towards statins (P < .001).
Conclusions:
Patients' perceived knowledge and receptivity towards statins may improve following participation in a comprehensive therapeutic lifestyle modification program. Future research must evaluate the impact of these programs on statin uptake, compliance and outcomes.
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