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Eponym: the Lemierre syndrome.

Efthimia G Vargiami1, D I Zafeiriou

  • 11st Pediatric Clinic, Aristotle University of Thessaloniki, Dorilaiou 3, Kalamaria, Thessaloniki, 55133, Greece. keva@med.auth.gr

European Journal of Pediatrics
|January 29, 2010
PubMed
Summary

Lemierre syndrome, or postanginal sepsis, is a severe complication of throat infections caused by Fusobacterium necrophorum. This "forgotten disease" is reemerging due to antibiotic resistance and decreased awareness.

Area of Science:

  • Infectious Diseases
  • Microbiology
  • Vascular Surgery

Background:

  • Lemierre syndrome, also known as postanginal sepsis, is a serious complication of oropharyngeal infections.
  • It involves septic thrombophlebitis of the internal jugular vein, leading to septicemia and potential metastatic infections.
  • Fusobacterium necrophorum, an oral commensal, is the typical causative agent.

Purpose of the Study:

  • To highlight the reemergence of Lemierre syndrome.
  • To underscore the importance of recognizing this potentially fatal condition.
  • To discuss the role of antibiotic resistance and decreased clinical awareness.

Main Methods:

  • Review of clinical presentations and causative agents of Lemierre syndrome.
  • Analysis of historical trends and current reemergence factors.

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  • Emphasis on diagnostic criteria and clinical suspicion.

    • Main Results:

    • Lemierre syndrome, once considered a

    Conclusions:

    • Despite its historical decline due to antibiotics, Lemierre syndrome is becoming more prevalent.
    • Increasing antibiotic resistance and reduced clinical awareness contribute to its reemergence.
    • Prompt diagnosis and treatment are crucial for managing this severe infection.