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Management of acute hematogenous osteomyelitis in children
Nada S Harik1, Mark S Smeltzer
1Department of Pediatrics and Department of Microbiology and Immunology, University of Arkansas for Medical Sciences and the Arkansas Children's Hospital, Little Rock, AR 72205, USA. hariknada@uams.edu
Insights
Acute hematogenous osteomyelitis in children is often caused by Staphylococcus aureus. Recent shifts in bacterial resistance, particularly community-associated methicillin-resistant Staphylococcus aureus, impact diagnosis and management strategies.
Area of Science:
- Pediatrics
- Infectious Diseases
- Orthopedics
Background:
- Osteomyelitis in children is typically acute and hematogenous.
- Staphylococcus aureus is the primary causative agent.
- Emergence of community-associated methicillin-resistant Staphylococcus aureus has altered infection dynamics.
Purpose of the Study:
- To review recent advancements in diagnosing acute hematogenous osteomyelitis in children.
- To discuss updated management strategies for pediatric osteomyelitis.
- To address the impact of evolving Staphylococcus aureus epidemiology.
Main Methods:
- Literature review focusing on recent studies.
- Analysis of epidemiological data on Staphylococcus aureus.
- Synthesis of current diagnostic and therapeutic guidelines.
Main Results:
- Increased prevalence of community-associated methicillin-resistant Staphylococcus aureus strains.
- Changes in clinical presentation and treatment resistance.
- Need for updated diagnostic criteria and therapeutic approaches.
Conclusions:
- Current diagnostic and management protocols require adaptation.
- Effective treatment necessitates consideration of antibiotic resistance patterns.
- Continued surveillance and research are crucial for pediatric osteomyelitis care.
Abstract:
In children, osteomyelitis is primarily hematogenous in origin and acute in nature. The principal cause of osteomyelitis in children is Staphylococcus aureus, and both the epidemiology and pathogenesis of S. aureus infections, including osteomyelitis, have changed in recent years owing to the emergence of community-associated methicillin-resistant S. aureus. This review focuses on advances in the diagnosis and overall management of acute hematogenous osteomyelitis in children with these changes in mind.
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