Related Experiment Video
Updated: Jun 16, 2026

A Streamlined, Label-Free Real-Time 50% Tissue Culture Infectious Dose (TCID50) Assay using Impedance for Automated Viral Titer Quantification
Published on: January 9, 2026
Comparability of bovine virus titers obtained by TCID50/ml and FAID50/ml
Han-Tse Lin1, Hong-Yuan Tsai, Chia-Pin Liu
1Testing Facility for Biological Safety, Taiwan.
Abstract:
In this study, the correlation or comparability was assessed in the values of virus titers measured by either infectivity assay [reported as 50% tissue culture infectious doses (TCID(50)/ml)] or by immunofluorescence assay [reported as 50% fluorescent antibody infectious dose (FAID(50)/ml)]. The results demonstrate that bovine virus titers measured in infected bovine turbinate cells by these two methods are comparable. Clear demonstration of the comparability of these two methods provides a choice of a method for measuring the titer of bovine viruses.

