The value of various definitions of intrathoracic goiter for predicting intra-operative and postoperative complications
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Updated: Jun 16, 2026

Minimal Invasive Resection of Large Retrosternal Thyroid Goiter
Published on: September 20, 2024
Antonio Ríos1, José M Rodríguez, María D Balsalobre
1Servicio de Cirugía General y del Aparato Digestivo I, Servicio de Endocrinologia y Nutrición, Hospital Universitario Virgen de la Arrixaca, El Palmar, Murcia, Spain. arzrios@teleline.es
Background:
Intrathoracic goiter (IG) is a pathologic and clinical entity defined by criteria that varies from one series to the next. The objective of this study was to determine the most useful definition of IG for predicting intra-operative and postoperative complications.
Methods:
The study included 201 patients treated for multinodular goiter who met the following criteria: (1) they had no previous thyroid surgery; (2) they had undergone total thyroidectomy; and (3) they were diagnosed with IG according to 1 of the following definitions: (1) clinical; (2) Hsu's; (3) Kocher's; (4) Torre's; (5) Eschapase's; (6) Lahey's; (7) Lindskog's; (8) Crile's; (9) Katlic's; and (10) subcarinal. Three variables were evaluated: (1) intra-operative complications; (2) need for a sternotomy; and (3) postoperative complications.
Results:
During orotracheal intubation, there were difficulties in 25 cases, all of which were detected using the 6 least restrictive definitions of IG (these range from the clinical definition to Lahey's definition. In 6 (3%) cases, it was necessary to carry out a sternotomy. The thoracic approach could be predicted using Katlic's definition. None of the definitions of IG was useful for predicting postoperative complications.
Conclusion:
Most definitions of IG can be ignored because they are not clinically relevant. The 6 least restrictive definitions overlap in their utility to predict intubation difficult during the anesthetic process; consequently, the clinical definition should be used because it is the simplest to calculate. Katlic's definition is the most useful for predicting a possible sternotomy for extirpating goiter.
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