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Updated: Jun 16, 2026

The Bovine Lung in Biomedical Research: Visually Guided Bronchoscopy, Intrabronchial Inoculation and In Vivo Sampling Techniques
Published on: July 3, 2014
Bovine coronavirus associated syndromes.
Mélanie J Boileau1, Sanjay Kapil
1Food Animal Medicine and Surgery, Department of Veterinary Clinical Sciences, Oklahoma State University Center for Veterinary Health Sciences, Stillwater, OK 74078, USA. melanie.boileau@okstate.edu
Bovine coronavirus causes respiratory and intestinal issues in cattle. This review covers its clinical signs, diagnosis, prevention, and treatment, highlighting limited genetic data.
Area of Science:
- Veterinary Virology
- Animal Health
- Coronaviruses
Background:
- Bovine coronaviruses (BCV) primarily affect the intestinal and respiratory tracts of cattle.
- Enteric and respiratory symptoms in cattle are linked to antigenically and genetically similar BCV strains.
- Limited genetic information exists for BCV due to only four fully sequenced isolates.
Purpose of the Study:
- To review clinical syndromes associated with bovine coronavirus.
- To discuss diagnostic methods for BCV infections.
- To outline prevention and treatment strategies for BCV.
Main Methods:
- Literature review of clinical syndromes, diagnostics, prevention, and treatment of bovine coronavirus.
- Analysis of existing data on BCV genetics and epidemiology.
Main Results:
- BCV is associated with pneumonia in calves and adult cattle, calf diarrhea, and winter dysentery.
- Diagnostic approaches for BCV are presented.
- Vaccination for prevention and immunotherapy for treatment are discussed.
Conclusions:
- Bovine coronavirus presents diverse clinical syndromes in cattle.
- Comprehensive diagnostic and management strategies are crucial for controlling BCV.
- Further research into BCV genetics is warranted.
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