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Updated: Mar 10, 2026

Quantitation of Rabies Virus in Various Bovine Brain Structures
Published on: May 22, 2021
Brainstem and Cranial Nerve Disorders of Ruminants
Mélanie J Boileau1, John Gilliam1
1Veterinary Clinical Sciences, College of Veterinary Medicine, Oklahoma State University, 2065 West Farm Road, Stillwater, OK 74078-2041, USA.
Abstract:
Asymmetrical signs of brainstem disease occur relatively infrequently in ruminants. The most common differential diagnoses include listeriosis, otitis media/interna, and pituitary abscess syndrome. Although these conditions produce signs of brainstem dysfunction, the diseases can usually be differentiated based on historical findings and subtle clinical differences. Basic laboratory diagnostic tests are often not specific in the definitive diagnosis but may be supportive. Advanced imaging techniques have proven to be useful in the diagnosis of otitis media/interna. Presumptive clinical diagnosis is confirmed at necropsy. Treatment involves a prolonged course of antibiotic therapy but is unrewarding in cases of pituitary abscess syndrome.
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