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Microarray Analysis for Saccharomyces cerevisiae
Published on: April 7, 2011
DNA microarray analysis of genomic responses of yeast Saccharomyces cerevisiae to nickel chloride
Shota Takumi1, Hirokazu Kimura, Hiromi Matsusaki
1Faculty of Environmental and Symbiotic Sciences, Prefectural University of Kumamoto.
The Journal of Toxicological Sciences
|February 2, 2010
Abstract:
In order to investigate nickel toxicity against the yeast Saccharomyces cerevisiae, genomic responses to nickel chloride were examined using yeast DNA microarrays. Microarray analysis revealed that exposure to 25 mM nickel chloride for 2 hr induced changes in gene expression in S. cerevisiae. Nickel chloride increased expression levels in 601 genes and decreased expression levels in 696 genes in S. cerevisiae.
