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[A case report of eosinophilic cystitis complicated with transient vesicoureteral reflux]
H Ogura1, M Gakiya, S Shishido
1Department of Urology, School of Medicine, University of the Ryukyu.
Insights
Eosinophilic cystitis in a young girl resolved with allergy treatment, improving bladder function and transient vesicoureteral reflux. This case highlights the link between allergies and urinary tract issues.
Area of Science:
- Pediatric Urology
- Allergology
- Pathology
Background:
- Eosinophilic cystitis is a rare bladder inflammation.
- Allergic disorders are increasingly recognized as potential triggers for various inflammatory conditions.
Observation:
- An 11-year-old girl with allergic disorders presented with symptoms of pollakisuria, painful urination, vesical irritability, and gross hematuria.
- Urinalysis revealed aseptic pyuria with 10% eosinophils, confirmed by urine cytology.
- Cystoscopy showed a tumorous lesion and edematous mucosa, while intravenous pyelography indicated bilateral hydronephrosis and a contracted bladder.
Findings:
- Bladder biopsies confirmed eosinophilic cystitis.
- Antiallergic treatment led to symptom resolution and restoration of normal bladder appearance and histology within 3 months.
- Transient vesicoureteral reflux significantly improved over 10 months.
Implications:
- This case suggests a potential link between allergic disorders and eosinophilic cystitis.
- Prompt diagnosis and management with antiallergic therapy can effectively treat eosinophilic cystitis and associated urinary abnormalities.
- Further research into the immunological mechanisms underlying eosinophilic cystitis in allergic individuals is warranted.
Abstract:
A case of eosinophilic cystitis complicated with transient vesicoureteral reflux in an 11-year-old girl with allergic disorders is reported. She was suffering from pollakisuria, painful urination, vesical irritability, and gross hematuria for about 2 months. Urinalysis showed aseptic pyuria. White blood cell count was 9,700/mm3 with eosinophils of 10%. Eosinophils were also found on urine cytology. Intravenous pyelography revealed bilateral hydronephrosis and apparently contracted bladder. Tumorous lesion and edematous mucosa were observed in the retrotrigonal region on cystoscopy. The multiple bladder biopsy uniformly revealed eosinophilic cystitis. Following antiallergic treatment, practically all symptoms subsided in steps, and normal cystoscopic appearance and histological structure were restored in 3 months. The vesicoureteral reflux markedly diminished in 10 months.