Related Experiment Video
Updated: Jun 16, 2026

Preparation of CD4+ T Cells for Analysis of GD3 and GD2 Ganglioside Membrane Expression by Microscopy
Published on: November 8, 2016
GQ1b ganglioside antibody-related disorders: a case with a complex phenotype
Y M Pers1, G Taïeb, X Ayrignac
1Department of Neurology, Caremeau Hospital, CHU Nîmes, France.
Abstract:
We described an overlap syndrome associating Miller Fisher syndrome (MFS) and acute inflammatory demyelinating polyradiculoneuropathy (AIDP). Furthermore, the patient presented unusual neurological manifestations including headache, T10 sensory level, urinary urgency, and gadolinium enhancement of the spinal roots. One year follow-up was characterized by clinical recovery and persistent high rates of anti-GQ1b, -GD1b and -GT1b antibodies. Our case suggests broad phenotype of persistent antigangliosides antibodies.
Related Concept Videos
Myasthenia Gravis ll: Pathophysiology
Pleiotropy
Proteoglycans
Myasthenia Gravis: Overview and Treatment
These antibodies interfere with the function of the nicotinic receptors in three ways: by binding to the receptor and disrupting acetylcholine binding; by causing cross-linking of receptors which leads...
Sex-linked Disorders
Pedigree Analysis

