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Updated: Jun 16, 2026
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Computerized Dynamic Posturography for Postural Control Assessment in Patients with Intermittent Claudication
Published on: December 11, 2013
Lower extremities' postthrombotic syndrome after total knee arthroplasty
Saradej Khuangsirikul1, Sudsriluk Sampatchalit, Trakool Foojareonyos
1Department of Orthopaedics, Phramongkutklao Hospital, Bangkok 10400, Thailand.
Summary
Patients who develop deep venous thrombosis (DVT) after total knee arthroplasty (TKA) have a higher risk of post-thrombotic syndrome (PTS). DVT prevention is crucial for reducing PTS risk following TKA.
Area of Science:
- Orthopedic Surgery
- Vascular Medicine
- Thrombosis Research
Background:
- Deep venous thrombosis (DVT) affects 40-60% of patients post-total knee arthroplasty (TKA).
- Post-thrombotic syndrome (PTS) is a frequent long-term complication of DVT, developing within months to years after the initial event.
Purpose of the Study:
- To evaluate the prevalence of PTS in TKA patients with and without a history of DVT.
- To assess the long-term outcomes of DVT after TKA over a minimum 2-year follow-up period.
Main Methods:
- Retrospective chart review of TKA patients (October 2002-2005).
- Postoperative assessment for PTS using Villalta score and duplex ultrasonography at >= 2 years.
- Confirmed DVT diagnosis via contrast venography.
Main Results:
- 22 of 76 patients (29%) developed PTS; 56 had previous DVT, 20 did not.
- Patients with prior DVT had a significantly higher risk of PTS (OR = 1.59; p=0.001).
- Venous reflux was detected in 36/56 (64%) of the previous DVT group and 8/20 (40%) of the non-previous DVT group, predominantly in the popliteal and posterior tibial veins.
Conclusions:
- DVT following TKA significantly increases the risk of developing PTS.
- Current DVT treatments may not fully mitigate the risk of PTS.
- Preventing DVT after TKA is essential for mitigating the long-term risk of PTS.
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