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Binding and interplay of HMG proteins on chromatin: lessons from live cell imaging

Fred Catez1, Robert Hock

  • 1Centre de Génétique Moléculaire et Cellulaire, CNRS UMR5534, 16 rue Dubois. F-69622 Villeurbanne, Université de Lyon, Lyon F-69003, France. frederic.catez@cgmc.univ-lyon.fr

Biochimica Et Biophysica Acta
|February 4, 2010
PubMed

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Chromatin Immunoprecipitation- ChIP

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Inheritance of Chromatin Structures

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The histone proteins have a flexible N-terminal tail extending out from the nucleosome. These histone tails are often subjected to post-translational modifications such as acetylation, methylation, phosphorylation, and ubiquitination. Particular combinations of these modifications form “histone codes” that influence the chromatin folding and tissue-specific gene expression.
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