Related Experiment Video
Updated: Jan 13, 2026

13:18
Optimization of the Longa Middle Cerebral Artery Occlusion Method for Complete Reperfusion
Published on: November 22, 2024
1.9K
Symptomatic delayed reocclusion after initial successful revascularization in acute ischemic stroke
Muhammad S Hussain1, Ridwan Lin, Shaye Moskowitz
1Cerebrovascular Center, Cleveland Clinic Foundation, Ohio 44195, USA.
Summary
Delayed symptomatic reocclusion can occur after endovascular stroke therapy, leading to sudden clinical decline. Careful patient assessment is crucial to identify and manage this complication effectively.
Area of Science:
- Neurology
- Interventional Cardiology
- Vascular Surgery
Background:
- Endovascular stroke therapy is a critical treatment for ischemic stroke.
- Acute reocclusion is a known complication that can negatively impact patient outcomes.
- This study investigates the incidence and consequences of delayed symptomatic reocclusion following endovascular interventions.
Observation:
- A review of 107 endovascular stroke interventions was conducted.
- Four patients (3.5%) experienced delayed symptomatic reocclusion.
- Reocclusion occurred 12 to 18 hours post-procedure, causing clinical deterioration.
Findings:
- Patients experiencing reocclusion had baseline NIHSS scores of 8-24.
- Initial successful recanalization was achieved in all affected patients.
- While re-treatment improved NIHSS scores, they did not reach pre-deterioration levels.
Implications:
- Delayed symptomatic reocclusion is a significant factor affecting outcomes after endovascular stroke therapy.
- This complication can be easily missed due to initial improvements and high baseline deficits.
- Close monitoring and careful assessment are essential for patients undergoing endovascular stroke treatment.

