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Brain tumors in children: a review
1Department of Neurology, North Shore University Hospital, Manhasset, NY 11030.
Annals of Clinical and Laboratory Science
|January 1, 1991
Summary
Childhood brain tumors, often glial, differ from adult types and some are curable. Advances in diagnostics like immunostaining and cytogenetics improve treatment outcomes for pediatric brain neoplasms.
Area of Science:
- Pediatric Oncology
- Neuro-oncology
- Childhood Malignancies
Background:
- Brain tumors represent the second most frequent childhood malignancy.
- Pediatric brain tumors are typically of glial origin, unlike adult tumors where metastases and meningiomas are more common.
- Certain tumors, such as medulloblastomas, are unique to children and frequently occur in the posterior fossa.
Purpose of the Study:
- To review significant pediatric brain tumors.
- To provide an update on recent advancements in the diagnosis and treatment of childhood brain neoplasms.
- To highlight the unique characteristics and prognoses of brain tumors in children.
Main Methods:
- Review of current literature on pediatric brain tumors.
- Discussion of diagnostic advancements including immunostaining, tumor markers, and cytogenetics.
- Analysis of treatment strategies and outcomes for childhood brain neoplasms.
Main Results:
- Childhood brain tumors exhibit distinct origins and common sites compared to adult tumors.
- Prognoses for pediatric neoplasms are generally more favorable, with some lesions being curable.
- Enhanced diagnostic accuracy has been achieved through new techniques.
Conclusions:
- Understanding the specific nature of childhood brain tumors is crucial for effective management.
- Recent developments in diagnostics and treatment offer improved outcomes for pediatric patients.
- Early and accurate diagnosis significantly impacts the curability and prognosis of childhood brain neoplasms.