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Related Experiment Video

Updated: Jun 16, 2026

Using the optokinetic response to study visual function of zebrafish
08:59

Using the optokinetic response to study visual function of zebrafish

Published on: February 2, 2010

Using the optokinetic response to study visual function of zebrafish.

Su-Qi Zou1, Wu Yin, Ming-Jing Zhang

  • 1Laboratory of Neurodevelopment and Repair, Department of Neurobiology and Biophysics, School of Life, University of Science and Technology of China, China.

Journal of Visualized Experiments : Jove
|February 4, 2010
PubMed
Summary
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We developed a new method to measure the optokinetic response (OKR) in adult zebrafish, enabling better investigation of their visual functions. This protocol is adaptable for both larval and adult zebrafish visual assessments.

Area of Science:

  • Neuroscience
  • Ophthalmology
  • Zebrafish models

Background:

  • Optokinetic response (OKR) is crucial for assessing visual function in larval zebrafish.
  • Standard OKR protocols are not easily transferable to adult zebrafish.
  • A need exists for reliable OKR measurement methods in adult zebrafish visual studies.

Purpose of the Study:

  • To introduce a novel, simple custom-built apparatus and protocol for measuring optokinetic response (OKR) in adult zebrafish.
  • To provide a detailed demonstration of the OKR measurement procedure for adult zebrafish.
  • To offer a valuable tool for investigating visual function in adult zebrafish, especially when the visual system is manipulated.

Main Methods:

  • Development of a simple custom-built apparatus for adult zebrafish OKR measurement.

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Related Experiment Videos

Last Updated: Jun 16, 2026

Using the optokinetic response to study visual function of zebrafish
08:59

Using the optokinetic response to study visual function of zebrafish

Published on: February 2, 2010

The Optokinetic Response as a Quantitative Measure of Visual Acuity in Zebrafish
04:56

The Optokinetic Response as a Quantitative Measure of Visual Acuity in Zebrafish

Published on: October 9, 2013

A Behavioral Assay to Measure Responsiveness of Zebrafish to Changes in Light Intensities
09:39

A Behavioral Assay to Measure Responsiveness of Zebrafish to Changes in Light Intensities

Published on: October 3, 2008

  • Establishment of a new laboratory protocol for conducting OKR tests in adult zebrafish.
  • Demonstration of both larval OKR and adult optomotor response (OMR) tests in conjunction with the adult OKR protocol.

    • Main Results:

    • The presented method allows for the measurement of OKR in adult zebrafish.
    • The custom apparatus and protocol are effective for adult zebrafish visual function assessment.
    • The OKR assay in adult fish can be conducted for up to 4 hours.

    Conclusions:

    • The developed custom apparatus and protocol provide an accessible method for measuring optokinetic response in adult zebrafish.
    • This new assay enhances the efficiency of visual function investigations in adult zebrafish models.
    • The protocol is versatile, also demonstrating larval OKR and adult optomotor response (OMR) for comprehensive visual function analysis.