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Updated: Jun 16, 2026

Robotically Delivered fMRI-Guided Personalized Transcranial Magnetic Stimulation Therapy for Treatment-Resistant Depression
Published on: April 10, 2026
Productivity losses among treated depressed patients relative to healthy controls
Suellen Curkendall1, Kimberly M Ruiz, Vijay Joish
1Thomson Reuters, 4301 Connecticut Avenue NW, Suite 330, Washington, DC 20008, USA. suellen.curkendall@thomsonreuters.com
Objectives:
Estimate the productivity-related cost of depression in an employed population.
Methods:
By using administrative data, annual short-term disability (STD) and absenteeism costs ($2005) were compared for patients with depression and treated with antidepressants and for a matched control group without depression.
Results:
Mean annual STD costs were $1038 among treated depressed patients versus $325 among controls and $1685 among a subgroup of severely depressed treated patients versus $340 among their controls. After controlling for demographic and employment characteristics, treated patients with depression had STD costs that were $356 higher per patient and those with severe depression had costs that were $861 higher. The marginal impact of treated depression on absenteeism was $377.
Conclusions:
Even when depressed patients are treated with antidepressants, there are substantial productivity losses. Therapies that can better manage depression may provide opportunities for savings to employers.
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