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Related Concept Videos

Hepatitis01:25

Hepatitis

Hepatitis is an inflammatory condition of the liver most commonly caused by hepatotropic viruses (A–E), though non-infectious causes such as alcohol and drugs also exist.Hepatitis AHepatitis A virus (HAV) is a non-enveloped RNA virus of the Picornaviridae family. It is primarily transmitted via the fecal-oral route, typically through ingestion of contaminated food or water. After ingestion, HAV enters the bloodstream through the oropharynx or intestinal epithelium and reaches the liver. The...
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Giardiasis is a globally prevalent intestinal infection caused by the protozoan parasite Giardia duodenalis (also known as G. lamblia or G. intestinalis). This flagellated protozoan is the most frequently identified intestinal parasite in the United States and worldwide. Transmission primarily occurs via the fecal-oral route, with infection arising from ingestion of water or food contaminated with cysts. Individuals in low-resource settings, international travelers, outdoor enthusiasts, daycare...
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Yellow fever is a viral hemorrhagic disease caused by the yellow fever virus (YFV), a member of the Flaviviridae family. It is transmitted primarily by Aedes and Haemagogus mosquitoes in tropical and subtropical regions of Africa and South America. After transmission through a mosquito bite, the virus initially replicates in skin-resident immune cells such as dendritic cells and macrophages. These cells then migrate to the lymph nodes, where viral replication increases, eventually leading to...

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Comparative Analysis of Automatic Fecal Analyzer versus Direct Wet Smear Microscopy for Detecting Parasitic Infections in Stool Samples
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Capillaria hepatica in China.

Chao-Ding Li1, Hui-Lin Yang, Ying Wang

  • 1Department of Orthopedics, First Affiliated Hospital of Soochow University, Soochow 215006, Jiangsu Province, China.

World Journal of Gastroenterology
|February 6, 2010
PubMed
Summary
This summary is machine-generated.

Capillaria hepatica (C. hepatica) is a parasitic nematode found in rodents, particularly rats, leading to liver damage. This review examines its biology, spread in China, and liver pathology to improve understanding and treatment.

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Area of Science:

  • Veterinary Parasitology
  • Hepatology
  • Epidemiology

Background:

  • Capillaria hepatica (C. hepatica) is a nematode parasite causing hepatic capillariasis in mammals.
  • Rodents, especially rats, are primary hosts, contributing to the global spread of C. hepatica.
  • The liver is the main site of infection, with parasite presence causing significant physical damage.

Purpose of the Study:

  • To review the biological characteristics and epidemiology of C. hepatica in China.
  • To detail the histopathologic changes in the liver caused by C. hepatica infection.
  • To enhance understanding of hepatic capillariasis for improved disease management and treatment strategies.

Main Methods:

  • Literature review focusing on ecological, anatomical, and clinical aspects of C. hepatica.
  • Analysis of epidemiological data specific to China.
  • Compilation of histopathological findings related to liver damage.

Main Results:

  • Rodents, particularly rats, are key hosts facilitating global dissemination.
  • C. hepatica infection primarily affects the liver, causing notable physical damage.
  • Clinical manifestations are often non-specific, leading to diagnostic challenges.

Conclusions:

  • Hepatic capillariasis poses a significant threat due to widespread rodent hosts and liver pathology.
  • Non-specific symptoms complicate clinical diagnosis, highlighting the need for increased awareness.
  • Further understanding of C. hepatica's biology and epidemiology in China is crucial for effective intervention.