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Health effects of vitamin D
1Centre on Aging and Mobility, University of Zurich and Department of Rheumatology and Institute of Physical Medicine, University Hospital Zurich, Switzerland. Heike.Bischoff@usz.ch
Abstract:
Increasing data suggest that many or most adults in the United States and Europe would benefit from vitamin D supplements. This review summarizes the benefits of vitamin D with the strongest evidence today from randomized controlled trials for fall and fracture prevention. Beyond fall and fracture prevention, vitamin D may also reduce overall morbidity by multiple mechanisms. Prospective epidemiological studies supported by strong mechanistic evidence suggest a reduction of cardiovascular disease (incident hypertension and cardiovascular mortality) and colorectal cancer, extending to weaker evidence on immune-modulatory and anti-inflammatory benefits of vitamin D.
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