Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Role of Skin in Vitamin D Synthesis01:23

Role of Skin in Vitamin D Synthesis

The skin plays a crucial role in the synthesis of vitamin D, a vital nutrient for various physiological processes in the body. Vitamin D is unique because it can be synthesized in the skin through a series of chemical reactions triggered by exposure to ultraviolet B (UVB) radiation from sunlight.
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin D3(cholecalciferol).
Connective Tissue Cell Types01:22

Connective Tissue Cell Types

Connective tissue develops from the mesoderm of a developing embryo and consists of cells, fibers, and ground substance: a gel-like material containing large complexes of carbohydrates and proteins. Connective tissue was first identified as a separate tissue family in the 18th century, and Johannes Peter Muller coined the term connective tissue.
Fat cells (adipocytes), smooth muscle cells (myoblasts), and bone cells (osteoblasts) are some connective tissue cell types. Some immune system cells...
Vitamins01:30

Vitamins

Vitamins, derived from the Latin word for life, are essential organic substances required in small quantities for optimal growth and overall well-being. Unlike other organic nutrients, vitamins don't act as sources of energy or building materials but rather facilitate these nutrients' utilization by the body. Vitamins are predominantly coenzymes, assisting enzymes in specific chemical actions, like the oxidation of glucose for energy involving B vitamins. Most vitamins are not produced in our...
Role of Vitamins in Maintaining Bone Health01:25

Role of Vitamins in Maintaining Bone Health

The growth and maintenance of bone are regulated by a combination of nutritional factors, including vitamins, such as vitamin A, B12, C, D, and K.
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...
Drug Therapy01:28

Drug Therapy

The advent of drug therapy has profoundly shaped modern mental health care, providing targeted treatments for a range of psychological disorders. Psychotherapeutic drugs, classified into antianxiety, antidepressant, and antipsychotic medications, address symptoms across anxiety disorders, mood disorders, and schizophrenia. While these medications have transformed patient outcomes, they require careful management due to their potential side effects and limitations.
Antianxiety Medications
Tumor Immunotherapy01:27

Tumor Immunotherapy

Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Prevalence of melasma, quality-of-life impact and social stigmatization.

Clinical and experimental dermatology·2026
Same author

A global health mandate for skin biology: Research opportunities for improved care after the World Health Assembly (WHA) skin diseases resolution.

The Journal of investigative dermatology·2026
Same author

What's New in Photoprotection?

American journal of clinical dermatology·2026
Same author

Understanding the Clinical Spectrum of the Cutaneous and Acute Hepatic Porphyrias.

American journal of clinical dermatology·2026
Same author

Biological Photoprotection: A Review of its Mechanisms, Evidence, and Clinical Implications.

Dermatology and therapy·2026
Same author

From Ultraviolet to Visible Light: Emerging Concepts in Comprehensive Photoprotection.

Photodermatology, photoimmunology & photomedicine·2026
Same journal

Increased Risk of Cutaneous T-Cell Lymphoma Development after Dupilumab Use for Atopic Dermatitis.

Dermatologic therapy·2024
Same journal

Correction to "Adjuvant PD-1 inhibitor versus high-dose interferon α-2b for Chinese patients with cutaneous and acral melanoma: A retrospective cohort analysis".

Dermatologic therapy·2022
Same journal

A case of erythema nodosum concomitant with ulcerative colitis relieved by tofacitinib.

Dermatologic therapy·2022
Same journal

A case report of vitiligo following toripalimab therapy for a patient with metastatic melanoma.

Dermatologic therapy·2022
Same journal

High versus low dose oral isotretinoin in the treatment of cutaneous and genital warts.

Dermatologic therapy·2022
Same journal

Evaluation of the efficacy and relapse rates of treatment protocols for moderate acne using isotretinoin based on the global acne grading system: Randomized, controlled, comparative study.

Dermatologic therapy·2022
See all related articles

Related Experiment Video

Updated: Jun 16, 2026

A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data
10:46

A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data

Published on: December 9, 2015

UV-based therapy and vitamin D.

Robert J Sage1, Henry W Lim

  • 1Department of Dermatology, Henry Ford Hospital, Detroit, Michigan 48202, USA.

Dermatologic Therapy
|February 9, 2010
PubMed
Summary
This summary is machine-generated.

Ultraviolet (UV) light therapy effectively treats skin conditions and impacts vitamin D levels. Further research is needed to determine if this offers protection against other health issues linked to low vitamin D.

More Related Videos

Studying Chronic Exposure of Mice to Ultraviolet B Radiation
03:20

Studying Chronic Exposure of Mice to Ultraviolet B Radiation

Published on: August 19, 2025

Related Experiment Videos

Last Updated: Jun 16, 2026

A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data
10:46

A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data

Published on: December 9, 2015

Studying Chronic Exposure of Mice to Ultraviolet B Radiation
03:20

Studying Chronic Exposure of Mice to Ultraviolet B Radiation

Published on: August 19, 2025

Area of Science:

  • Dermatology
  • Photobiology
  • Endocrinology

Background:

  • Ultraviolet (UV) light affects skin biology.
  • Phototherapy and photochemotherapy are established treatments for cutaneous disorders.
  • These therapies have good safety profiles but require resources and patient preparation.

Purpose of the Study:

  • To review the therapeutic benefits of UV light for skin conditions.
  • To examine the impact of UVB phototherapy on vitamin D levels.
  • To explore potential health benefits related to vitamin D status in patients undergoing phototherapy.

Main Methods:

  • Literature review of phototherapy and photochemotherapy efficacy.
  • Analysis of studies on UV light's effect on vitamin D synthesis.
  • Discussion of emerging research linking vitamin D to various health conditions.

Main Results:

  • Phototherapy offers significant relief for many skin diseases.
  • UVB exposure influences vitamin D levels.
  • The protective role of phototherapy-induced vitamin D against other diseases is currently unknown.

Conclusions:

  • UV light therapies are valuable for dermatological treatment.
  • The impact on vitamin D warrants further investigation for broader health implications.
  • More research is necessary to establish the link between phototherapy, vitamin D, and systemic health protection.