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Updated: Dec 13, 2025
Closure of a Patent Foramen Ovale PFO: An Intervention Sequence
Published on: December 23, 2022
[Experience of transcather closure in patients with postinfarction ventricular septal defects]
Yong Sun1, Jie Yuan, Ruo-Xi Zhang
1Department of Cardiovascular Diseases, Second Affiliated Hospital of Harbin Medical University, Harbin 150086, China.
Objective:
To evaluate the therapeutic effect of transcather closure in patients with postinfarction ventricular septal defects (VSD).
Methods:
Transcatheter VSD closure was performed in 12 patients with postinfarction VSD (10 muscular and 2 membranes defects) on top of standard pharmacotherapy and percutaneous transluminal coronary angioplasty (PTCA) as indicated.
Results:
(1) Percutaneous interventional VSD closure was successful in 9 out 12 patients (75%) and these 9 patients survived post procedure. (2) The medial time between VSD occurrence and closure was (15.5 +/- 9.2) days. Procedure-related complications such as device embolization and malignant arrhythmia occurred in 3 patients (25%). The medial time between procedure and discharge from hospital was (11.3 +/- 5.2) days. (3) Coronary angiography was performed in 2 patients and 4 stents were implanted in diseased lesions.
Conclusion:
Transcatheter closure could be successfully performed in selected patients with postinfarction VSD.
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