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Updated: Jun 16, 2026
07:37
Basic Research in Plasma Medicine - A Throughput Approach from Liquids to Cells
Published on: November 17, 2017
Improving availability and affordability of plasma-derived medicines
Abdol Majid Cheraghali1, Hassan Abolghasemi
1Iranian Blood Transfusion Organization Research Center, Tehran, Iran.
Summary
Plasma-derived medicines are crucial for treating serious diseases but are often unaffordable. Contract fractionation of local plasma offers an effective strategy to improve access and affordability globally.
Area of Science:
- Biochemistry and Biotechnology
- Pharmacology and Therapeutics
- Public Health and Global Medicine
Background:
- Plasma-derived medicines are vital for treating numerous life-threatening conditions.
- Over 25 plasma-derived products are commercially available, with some on the WHO Model List of Essential Medicines.
- High treatment costs limit patient access, particularly in developing nations.
Purpose of the Study:
- To explore strategies for enhancing the accessibility and affordability of plasma-derived medicines.
- To evaluate the effectiveness of different approaches, including local production, importation, and contract fractionation.
- To highlight contract fractionation as a key solution for global access.
Main Methods:
- Review of current practices in plasma-derived medicine procurement and distribution.
- Analysis of the economic impact and logistical feasibility of various accessibility strategies.
- Case study examination of countries utilizing contract fractionation.
Main Results:
- Contract fractionation of locally sourced plasma has emerged as a highly effective method.
- This approach significantly improves both the availability and affordability of essential plasma-derived therapies.
- It presents a viable solution for overcoming cost barriers in resource-limited settings.
Conclusions:
- Contract fractionation is a critical strategy for ensuring equitable access to life-saving plasma-derived medicines.
- This model enhances national healthcare capabilities and patient outcomes.
- Global health initiatives should consider promoting contract fractionation for plasma products.
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