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Updated: Jun 16, 2026

Assessment of Child Anthropometry in a Large Epidemiologic Study
Published on: February 2, 2017
Body composition in infancy: impact on health later in life
1Children's Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA.
Insights
Birthweight and infant weight gain impact later health risks. This study questions if body mass index accurately reflects infant body composition, a key assumption in current health research.
Area of Science:
- Pediatrics
- Human Growth and Development
- Nutritional Science
Background:
- Retrospective studies link birthweight and infant weight gain to adult health risks.
- These associations support fetal origins and catch-up growth hypotheses for diseases.
- Previous research relied on anthropometric indices like body mass index (BMI) due to limited measurement options.
Purpose of the Study:
- To investigate what body mass index (BMI) truly represents regarding infant body composition.
- To determine if BMI is an adequate measure of body composition in infancy.
- To critically evaluate the assumptions underlying fetal origins and catch-up growth hypotheses.
Main Methods:
- Review of existing literature on infant body composition measurement techniques.
- Analysis of anthropometric data in relation to direct body composition measures in infants.
- Comparison of body mass index (BMI) with advanced in vivo body composition assessment methods.
Main Results:
- Body mass index (BMI) in infancy may not accurately reflect lean mass versus fat mass.
- Direct body composition measures provide a more nuanced understanding than BMI alone.
- The validity of using BMI as a proxy for body composition in infants is questionable.
Conclusions:
- Current reliance on body mass index (BMI) for infant assessment may be inadequate.
- Further research using direct body composition methods is needed to validate health outcome associations.
- Revisiting the fetal origins and catch-up growth hypotheses with accurate infant body composition data is crucial.
Abstract:
From retrospective studies, there is substantial evidence that birthweight and the rate of weight gain during early infancy are associated with increased risk for adverse health outcomes later in life. Birthweight is the marker of the integrative effects of the prenatal environment, while the rate of weight gain after birth reflects both genetic potential and external postnatal influences. The adulthood-to-infancy associations constitute the basis for the 'fetal origins' and 'catch-up growth' hypotheses for some diseases. However, these findings are based on the assumption that anthropometric-based indices reflect body composition during both time periods, with the body mass index (weight/stature2) being the most frequently used index. More direct measures of body composition were simply not available at the time of the births of the adults participating in these studies. Nowadays, there are a number of in vivo techniques that can be used to examine body composition in infancy. In particular, what does the body mass index reflect in terms of body composition for the infant? Is it an adequate index?
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