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[Dose-dependent effects of neuroimmunomodulator interferon alpha on behavior of humans and animals]

E V Loseva, N A Loginova, I G Akmaev

    Rossiiskii Fiziologicheskii Zhurnal Imeni I.M. Sechenova
    |February 10, 2010
    PubMed

    The review analyses the literature on polyfunctional activity of the cytokine interferon-alpha (IA) which has neuroimmunomodulatory properties and is used for treatment of viral and oncologic diseases. The major intention is devoted to action of small and high doses of IA on different forms of animals and human behavior. We suggest that chronic treatment with small IA doses is more effective than high dose therapy.

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