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Updated: Dec 25, 2025

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Kinetic Screening of Nuclease Activity using Nucleic Acid Probes
Published on: November 1, 2019
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On-bead library screening made easier
1Department of Chemistry, The Ohio State University, 100 West 18th Avenue, Columbus, OH 43210, USA.
Chemistry & Biology
|February 10, 2010
Abstract:
In this issue of Chemistry & Biology, Astle et al. report the rapid identification of the most active hits from a large one-bead-one-compound peptoid library by magnetic sorting and without the need for labor-intensive resynthesis of the hits.

