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Updated: Jun 16, 2026

High-Throughput Transcriptome Analysis for Investigating Host-Pathogen Interactions
Published on: March 5, 2022
Integration of 'omics' data: does it lead to new insights into host-microbe interactions?
Gwendoline Kint1, Carolina Fierro, Kathleen Marchal
1Centre of Microbial & Plant Genetics, KU Leuven, Kasteelpark Arenberg 20, B-3001 Leuven, Belgium. gwendoline.kint@biw.kuleuven.be
Abstract:
The interaction between both beneficial and pathogenic microbes and their host has been the subject of many studies. Although the field of systems biology is rapidly evolving, the use of a systems biology approach by means of high-throughput techniques to study host-microbe interactions is just beginning to be explored. In this review, we discuss some of the most recently developed high-throughput 'omics' techniques and their use in the context of host-microbe interaction. Moreover, we highlight studies combining several techniques that are pioneering the integration of 'omics' data related to host-microbe interactions. Finally, we list the major challenges ahead for successful systems biology research on host-microbe interactions.
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