Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Role of Cerebellum and Prefrontal Cortex in Memory

Role of Cerebellum and Prefrontal Cortex in Memory

The cerebellum, while traditionally associated with motor control, also plays a crucial role in memory, particularly in procedural memory, which involves learning motor tasks that become automatic through repetition. For example, studies have shown that when the cerebellum is damaged, individuals or animals lose the ability to learn conditioned motor responses, such as the conditioned eye-blink response in classical conditioning experiments with rabbits. This study demonstrates the cerebellum's...

Visual Agnosia

Visual Agnosia

Visual agnosia is a condition characterized by the inability to recognize visually presented objects despite having normal vision. For instance, a person with visual agnosia can describe the shape and color of an object but cannot identify or name it. This impairment does not affect their visual field, acuity, color vision, brightness discrimination, language, or memory. An example of this condition in a social setting is someone at a dinner party asking for "that silver thing with a round end"...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Correction: Cognitive load-dependent effects of HD-tDCS on the executive vigilance decrement: insights from aperiodic EEG activity.

Frontiers in cognition·2026

Same author

Cognitive load-dependent effects of HD-tDCS on the executive vigilance decrement: insights from aperiodic EEG activity.

Frontiers in cognition·2026

Same author

Understanding vigilance and its decrement: theoretical, contextual, and neural insights.

Frontiers in cognition·2026

Same author

The Effect of Sex and Gender-Role on Social Attention: Investigating the Association With Social Skills and Academic Preferences.

International journal of psychology : Journal international de psychologie·2026

Same author

When arrows behave like eyes: Reversal of spatial stroop interference by visual masking.

Cognition·2026

Same author

Attention and vigilance advantages related to formal musical training across childhood, adolescence and young adulthood.

British journal of psychology (London, England : 1953)·2026

Same journal

SMPD4 deficiency disrupts indirect neurogenesis and neuronal migration in gyrencephalic cortex.

Brain : a journal of neurology·2026

Same journal

Retinal hyper-reflective foci link retinal and cortical pathology in paediatric multiple sclerosis.

Brain : a journal of neurology·2026

Same journal

Two scripts, two pathways: dorsal-ventral biases in post-stroke kana-kanji agraphia.

Brain : a journal of neurology·2026

Same journal

Blood cytotoxic natural killer-like CD8 + CD94+ T cells migrate to the brain and predict multiple sclerosis severity.

Brain : a journal of neurology·2026

Same journal

Time to reconsider risk for psychosis?

Brain : a journal of neurology·2026

Same journal

A descending posterior insular pathway drives sensory hypersensitivity in neuropathic pain.

Brain : a journal of neurology·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Jun 16, 2026

The Dig Task: A Simple Scent Discrimination Reveals Deficits Following Frontal Brain Damage

The Dig Task: A Simple Scent Discrimination Reveals Deficits Following Frontal Brain Damage

Published on: January 4, 2013

Temporal orienting deficit after prefrontal damage.

Mónica Triviño¹, Angel Correa, Marisa Arnedo

¹Servicio de Neuropsicología, Hospital Universitario San Rafael, and Departamento de Psicología Experimental y Fisiología del Comportamiento, Universidad de Granada, c/ San Juan de Dios, 19, 18001 Granada, Spain. mtrivino@ugr.es

Brain : a Journal of Neurology

|February 11, 2010

Summary

This summary is machine-generated.

Patients with right prefrontal lesions struggle with temporal orienting of attention, indicating this cognitive function relies on the prefrontal cortex. Basal ganglia lesions did not impact temporal preparation effects.

More Related Videos

Eye Movements in Visual Duration Perception: Disentangling Stimulus from Time in Predecisional Processes

Eye Movements in Visual Duration Perception: Disentangling Stimulus from Time in Predecisional Processes

Published on: January 19, 2024

Anteromesial Temporal Lobectomy for Medically Intractable Temporal Lobe Epilepsy: An Operative Study

Anteromesial Temporal Lobectomy for Medically Intractable Temporal Lobe Epilepsy: An Operative Study

Published on: August 15, 2025

Related Experiment Videos

Last Updated: Jun 16, 2026

The Dig Task: A Simple Scent Discrimination Reveals Deficits Following Frontal Brain Damage

The Dig Task: A Simple Scent Discrimination Reveals Deficits Following Frontal Brain Damage

Published on: January 4, 2013

Eye Movements in Visual Duration Perception: Disentangling Stimulus from Time in Predecisional Processes

Eye Movements in Visual Duration Perception: Disentangling Stimulus from Time in Predecisional Processes

Published on: January 19, 2024

Anteromesial Temporal Lobectomy for Medically Intractable Temporal Lobe Epilepsy: An Operative Study

Anteromesial Temporal Lobectomy for Medically Intractable Temporal Lobe Epilepsy: An Operative Study

Published on: August 15, 2025

Area of Science:

Neuroscience
Cognitive Psychology
Neurology

Background:

Temporal preparation, encompassing temporal orienting, foreperiod, and sequential effects, is crucial for efficient cognitive processing.
The neural underpinnings of these temporal preparation effects, particularly their reliance on specific brain regions like the prefrontal cortex and basal ganglia, remain incompletely understood.

Purpose of the Study:

To investigate the neural basis of temporal orienting of attention in patients with brain lesions.
To examine the relationship between temporal orienting, foreperiod effect, and sequential effects.
To differentiate the roles of the prefrontal cortex and basal ganglia in temporal preparation.

Main Methods:

An experimental task involving temporal cueing (short/long line) and manipulated cue-target intervals (400/1400 ms) was administered.
Participants included 14 patients with prefrontal lesions, 15 healthy controls, and 7 patients with basal ganglia lesions.

Main Results:

Patients with right prefrontal lesions exhibited significant deficits in temporal orienting of attention compared to controls.
Prefrontal lesion patients also showed impairments in the foreperiod effect, but not sequential effects.
Patients with basal ganglia lesions did not display deficits in any of the temporal preparation effects.

Conclusions:

Temporal orienting and foreperiod effects are voluntary and strategic, critically depending on prefrontal cortex function.
Sequential effects appear to be more automatic, not requiring prefrontal cortex or frontobasal circuits.
These findings highlight the distinct neural substrates for different temporal preparation mechanisms.