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siRNA - Small Interfering RNAs02:30

siRNA - Small Interfering RNAs

Small interfering RNAs, or siRNAs, are short regulatory RNA molecules that can silence genes post-transcriptionally, as well as the transcriptional level in some cases. siRNAs are important for protecting cells against viral infections and silencing transposable genetic elements.
In the cytoplasm, siRNA is processed from a double-stranded RNA, which comes from either endogenous DNA transcription or exogenous sources like a virus. This double-stranded RNA is then cleaved by the ATP-dependent...

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Updated: Jun 16, 2026

Porous Silicon Microparticles for Delivery of siRNA Therapeutics
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Published on: January 15, 2015

Systemic siRNA delivery using biocompatible calcium phosphate nanoparticles

Kinam Park1

  • 1Purdue University, Department of Biomedical Engineering and Pharmaceutics, West Lafayette, Indiana, USA. kpark@purdue.edu

Journal of Controlled Release : Official Journal of the Controlled Release Society
|February 13, 2010
PubMed
Summary

No abstract available in PubMed .

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