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Developmental appearance of proteins identified by two-dimensional gel electrophoresis in mouse gonadal tissue
E J Durbin1, R P Erickson, M L Van Keuren
1Department of Human Genetics, University of Michigan School of Medicine, Ann Arbor.
Molecular Reproduction and Development
|March 1, 1991
Abstract:
Gonadal protein patterns of the mouse were studied during fetal development by two-dimensional gel electrophoresis. Fetal mice at days 8.5, 10.5, 12.5, and 14.5 post-coitum were analyzed for male or female specific proteins. Although no sex specific proteins were found, several proteins were found which were expressed in significantly different amounts in the two sexes at about the time of gonadal differentiation. Hence, quantitative differences, rather than qualitative ones, could be related to the initiation of testis or ovary development.