Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Effect of hyperprolactinemia on pituitary-adrenal function.

J M Feldman, J W Plonk

    Hormone Research
    |January 1, 1978
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Associations between asthma trigger reports, mental health conditions, and asthma morbidity among world trade center rescue and recovery workers.

    The Journal of asthma : official journal of the Association for the Care of Asthma·2018
    Same author

    A simple strategy for faster induction and more cost-effective use of anesthetic vapor.

    Journal of clinical monitoring and computing·2003
    Same author

    Compliance compensation of the Narkomed 6000 explained.

    Anesthesiology·2001
    Same author

    Gastrointestinal carcinoids: characterization by site of origin and hormone production.

    Annals of surgery·2000
    Same author

    Foregut carcinoids: a clinical and biochemical analysis.

    Surgery·1999
    Same author

    Carcinoids of unknown origin: comparative analysis with foregut, midgut, and hindgut carcinoids.

    Surgery·1998
    Same journal

    Abstracts of the LWPES/ESPE 8th Joint Meeting Global Care in Paediatric Endocrinology, in collaboration with APEG, APPES, JSPE and SLEP. New York City, New York, USA. September 9-12, 2009.

    Hormone research·2011
    Same journal

    Abstracts of the 47th Annual Meeting of the European Society for Paediatric Endocrinology (ESPE). Istanbul, Turkey. September 20-23, 2008.

    Hormone research·2011
    Same journal

    Abstracts of the 46th Annual Meeting of the European Society for Paediatric Endocrinology (ESPE). Helsinki, Finland. June 27-30, 2007.

    Hormone research·2011
    Same journal

    Genetic and pathogenetic aspects of Noonan syndrome and related disorders.

    Hormone research·2009
    Same journal

    Response to growth hormone in short children with Noonan syndrome: correlation to genotype.

    Hormone research·2009
    Same journal

    Growth hormone and the heart in Noonan syndrome.

    Hormone research·2009
    See all related articles

    Hyperprolactinemia, a condition of high prolactin levels, likely does not affect the hypothalamic-pituitary-adrenal axis. Studies on patients with pituitary tumors or hypothalamic issues showed normal adrenal responsiveness.

    Area of Science:

    • Endocrinology
    • Neuroendocrinology
    • Hormonal regulation

    Background:

    • Hyperprolactinemia is a common endocrine disorder often caused by pituitary tumors or hypothalamic dysfunction.
    • The hypothalamic-pituitary-adrenal (HPA) axis regulates the body's response to stress and maintains homeostasis.
    • Understanding potential interactions between hyperprolactinemia and HPA axis function is crucial for comprehensive patient management.

    Observation:

    • Three patients with hyperprolactinemia (two with pituitary tumors, one with hypothalamic disturbance) were assessed.
    • HPA axis function was evaluated using adrenocorticotropic hormone (ACTH), metyrapone testing, and insulin tolerance tests.
    • Adrenal responsiveness was measured through these endocrine function tests.

    Findings:

    Related Experiment Videos

  • No significant alterations in adrenal responsiveness were observed in the evaluated patients.
  • One patient showed a minor increase in adrenal response to pharmacological ACTH doses.
  • The study suggests hyperprolactinemia does not systematically impair HPA axis function.

    • Implications:

    • These findings indicate that hyperprolactinemia may not significantly disrupt the HPA axis in most cases.
    • Further research with larger cohorts is warranted to confirm these observations.
    • This understanding can inform clinical decision-making regarding the assessment and management of patients with hyperprolactinemia.