Charles S. Mott Prize. Recessive mutations in the causation of human cancer

IGFBP2 potentiates nuclear EGFR-STAT3 signaling.

Oncogene·2015

Neutralizing the EGF receptor in glioblastoma cells stimulates cell migration by activating uPAR-initiated cell signaling.

Oncogene·2014

EGFRvIII stimulates glioma growth and invasion through PKA-dependent serine phosphorylation of Dock180.

Oncogene·2013

Targeting EGFR for treatment of glioblastoma: molecular basis to overcome resistance.

Current cancer drug targets·2012

EGFRvIII promotes glioma angiogenesis and growth through the NF-κB, interleukin-8 pathway.

Oncogene·2011

Vascular endothelial growth factor isoforms display distinct activities in promoting tumor angiogenesis at different anatomic sites.

Cancer research·2001

Redefining leptomeningeal metastasis in non-small cell lung cancer: From terminal complication to molecularly managed disease.

Cancer·2026

Targeting RAS in pancreatic cancer.

Cancer·2026

Phase 1 dose escalation and expansion trial of the bispecific CD47 inhibitor and CD40 agonist Fc-fusion protein SL-172154 (SIRPα-Fc-CD40L) in patients with higher-risk myelodysplastic syndrome or acute myeloid leukemia.

Cancer·2026

Current challenges and emerging therapeutic strategies in lung cancer care: Insights from Bridging the Gaps 2025.

Cancer·2026

Progression-free survival and overall survival in the first-line treatment of BRCA wild-type advanced epithelial ovarian cancer: An analysis of patient-level data pooled from historical clinical trials.

Cancer·2026

Trends in sociodemographic factors associated with human papillomavirus vaccine hesitancy in the United States: 2010-2022.

Cancer·2026

Exposure-shaped immunometabolic networks in chronic liver disease: translating multi-omics and artificial intelligence into preventive biomarkers.

Frontiers in immunology·2026

The impact of deep learning and omics data in transforming precision therapy for brain cancer.

Frontiers in bioinformatics·2026

Intratumoral Microbiota in Fueling Cancer and Steering Treatment Response.

MedComm·2026

Global variability in colorectal cancer screening guidelines: panel composition and recommendations.

Journal of the Canadian Association of Gastroenterology·2026

Correction: A preliminary exploration of the mechanism of endometrial cancer development induced by intestinal flora diversity and its metabolites.

Frontiers in cellular and infection microbiology·2026

Real world genomic profiling in non-small cell lung cancer reveals regional variations with clinical implications.

Frontiers in oncology·2026

Related Experiment Videos

Charles S. Mott Prize. Recessive mutations in the causation of human cancer

Related Concept Videos

IGFBP2 potentiates nuclear EGFR-STAT3 signaling.

Neutralizing the EGF receptor in glioblastoma cells stimulates cell migration by activating uPAR-initiated cell signaling.

EGFRvIII stimulates glioma growth and invasion through PKA-dependent serine phosphorylation of Dock180.

Targeting EGFR for treatment of glioblastoma: molecular basis to overcome resistance.

EGFRvIII promotes glioma angiogenesis and growth through the NF-κB, interleukin-8 pathway.

Vascular endothelial growth factor isoforms display distinct activities in promoting tumor angiogenesis at different anatomic sites.

Redefining leptomeningeal metastasis in non-small cell lung cancer: From terminal complication to molecularly managed disease.

Targeting RAS in pancreatic cancer.

Phase 1 dose escalation and expansion trial of the bispecific CD47 inhibitor and CD40 agonist Fc-fusion protein SL-172154 (SIRPα-Fc-CD40L) in patients with higher-risk myelodysplastic syndrome or acute myeloid leukemia.

Current challenges and emerging therapeutic strategies in lung cancer care: Insights from Bridging the Gaps 2025.

Progression-free survival and overall survival in the first-line treatment of BRCA wild-type advanced epithelial ovarian cancer: An analysis of patient-level data pooled from historical clinical trials.

Trends in sociodemographic factors associated with human papillomavirus vaccine hesitancy in the United States: 2010-2022.

Exposure-shaped immunometabolic networks in chronic liver disease: translating multi-omics and artificial intelligence into preventive biomarkers.

The impact of deep learning and omics data in transforming precision therapy for brain cancer.

Intratumoral Microbiota in Fueling Cancer and Steering Treatment Response.

Global variability in colorectal cancer screening guidelines: panel composition and recommendations.

Correction: A preliminary exploration of the mechanism of endometrial cancer development induced by intestinal flora diversity and its metabolites.

Real world genomic profiling in non-small cell lung cancer reveals regional variations with clinical implications.

Related Experiment Videos

Charles S. Mott Prize. Recessive mutations in the causation of human cancer

Related Concept Videos

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