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Related Experiment Video

Updated: Jun 16, 2026

Transcranial Direct Current Stimulation for Online Gamers
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Published on: November 9, 2019

Pathological Gambling: Biological and Clinical Considerations.

Jocelyn L Topf1, Sarah W Yip, Marc N Potenza

  • 1Departments of Psychiatry and Child Study Center, Yale University School of Medicine, Connecticut Mental Health Center, New Haven, CT, United States.

Journal of Addiction Medicine
|February 18, 2010
PubMed
Summary

Pathological gambling, an impulse control disorder, shares similarities with substance use disorders. Treatments effective for substance use disorders show promise for treating pathological gambling.

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Area of Science:

  • Neuroscience
  • Psychiatry
  • Behavioral Science

Background:

  • Pathological gambling (PG) is classified as an impulse control disorder (ICD).
  • Evidence suggests overlapping pathophysiological mechanisms between substance use disorders (SUDs) and PG.
  • Similarities are observed in phenomenological, neurobiological, and pharmacological data.

Purpose of the Study:

  • To review biological findings in PG.
  • To summarize evidence-based treatment approaches for PG.
  • To explore the relationship between PG and SUDs.

Main Methods:

  • Literature review of biological studies on PG.
  • Analysis of controlled studies on PG treatment.
  • Comparison of PG and SUDs pathophysiology.

Main Results:

  • Biological studies reveal commonalities between PG and SUDs.
  • Behavioral and pharmacological treatments validated for SUDs show efficacy in PG.
  • Empirical data supports treatment interventions for PG.

Conclusions:

  • PG and SUDs share significant pathophysiological characteristics.
  • Treatments successful in SUDs management are applicable to PG.
  • Further research into neurobiological underpinnings can inform PG treatment strategies.