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Single Cell Measurements of Vacuolar Rupture Caused by Intracellular Pathogens
Published on: June 12, 2013
Synthesis of labeled meropenem for the analysis of M. tuberculosis transpeptidases
David B Kastrinsky1, Clifton E Barry
1The National Institutes of Health, National Institute of Allergy and Infectous Diseases, Tuberculosis Research Section, Bethesda MD 20892.
Tetrahedron Letters
|February 18, 2010
Abstract:
A concise synthesis of (14)C labeled meropenem prepared from (14)C dimethylamine hydrochloride is described. Using a similar reaction sequence, the meropenem nucleus was also attached to biotin providing a probe for protein interaction studies.
