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Stem Cell Culture

Stem Cell Culture

Stem cell research aims to find ways to use stem cells to regenerate and repair cellular damage. Over time, most adult cells undergo the wear and tear of aging and lose their ability to divide and repair themselves. Stem cells do not display a particular morphology or function. Adult stem cells, which exist as a small subset of cells in most tissues, keep dividing and can differentiate into a number of specialized cells generally formed by that tissue. These cells enable the body to renew and...

Embryonic Stem Cells

Embryonic Stem Cells

Embryonic stem (ES) cells were first discovered in mice in 1981 by Martin Evans. In 1998, James Thomson identified a method to isolate embryonic stem cells from humans. Human embryonic stem cells (hESCs) are obtained from 3-5 day old embryos that remain unused after an in vitro fertilization procedure.
ES cells are grown in a culture medium where they can divide indefinitely, creating ES cell lines. Under certain conditions, ES cells can differentiate, either spontaneously into a variety of...

Embryonic Stem Cells

Embryonic Stem Cells

Embryonic stem (ES) cells are undifferentiated pluripotent cells, meaning they can produce any cell type in the body. This gives them tremendous potential in science and medicine since they can generate specific cell types for use in research or to replace body cells lost due to damage or disease.

Maintenance of the ES Cell State

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The cells of the blastocyst inner cell mass only remain pluripotent for a short time. This state of pluripotency and self-renewal can be maintained in embryonic stem (ES) cell culture by adding specific chemicals or growth factors to ensure the cells can continue dividing and later differentiate into different cell types. In some cases, the cells are grown on a feeder layer of differentiated cells, which provides the growth factors and extracellular matrix components necessary for stem cell...

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Stem cells are undifferentiated cells with extensive self-renewal properties that help them maintain their population during the fetal and adult stages of life. They can specialize in all cell types of the human body. However, their differential potential may vary and can be classified into five types. Stem cells can be (1) Totipotent, (2) Pluripotent, (3) Multipotent, (4) Oligopotent, and (5) Unipotent. Each stem cell has a specific origin; the fertilized egg or zygote is a totipotent cell and...

Stem Cell Therapy for Tissue Regeneration

Stem Cell Therapy for Tissue Regeneration

Stem cell therapy is a method used in regenerative medicine to repair and restore function to damaged tissues and organs. Stem cells have the potential to proliferate and differentiate into various tissue types, making them ideal candidates for tissue regeneration. For example, hematopoietic stem cell transplants are commonly used in blood cancer treatment to replenish damaged bone marrow and restore healthy blood cells.
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Related Experiment Video

Updated: Jun 16, 2026

Single-Cell Sorting of Immunophenotyped Mesenchymal Stem Cells from Human Exfoliated Deciduous Teeth

Single-Cell Sorting of Immunophenotyped Mesenchymal Stem Cells from Human Exfoliated Deciduous Teeth

Published on: November 10, 2023

Stem Cells: It's Good To Have Choices.

Ian H Bellayr¹, Yong Li

¹Children's Hospital of the University of Pittsburgh Medical Center, Pittsburgh, PA, USA ; University of Pittsburgh, Pittsburgh, PA, USA.

The Journal of the American College of Certified Wound Specialists

|February 18, 2010

Summary

This summary is machine-generated.

New policies allow expanded stem cell research, including embryonic, adult, and induced pluripotent stem cells. This shift aims to advance stem cell treatments for various disorders.

Keywords:

Adult Stem Cells Embryonic Stem Cells Induced Pluripotent Stem Cells

Related Experiment Videos

Last Updated: Jun 16, 2026

Single-Cell Sorting of Immunophenotyped Mesenchymal Stem Cells from Human Exfoliated Deciduous Teeth

Single-Cell Sorting of Immunophenotyped Mesenchymal Stem Cells from Human Exfoliated Deciduous Teeth

Published on: November 10, 2023

Area of Science:

Regenerative Medicine
Developmental Biology
Biomedical Research Policy

Background:

Current stem cell research involves embryonic, adult, and induced pluripotent stem cells.
Previous federal policies under the Bush administration restricted stem cell research funding.
The Obama administration's actions have initiated a review of these restrictions.

Purpose of the Study:

To outline the policy changes affecting stem cell research funding.
To highlight the increased freedom for researchers utilizing stem cells.
To emphasize the goal of identifying optimal stem cell treatments for disorders.

Main Methods:

Analysis of policy changes initiated by the Obama administration.
Review of National Institute of Health (NIH) funding distribution guidelines.
Assessment of the impact on research freedom and therapeutic development.

Main Results:

Revocation of previous executive orders and statements concerning stem cell research.
Establishment of a provisional period for NIH policy revision.
Anticipation of expanded research opportunities and therapeutic innovation.

Conclusions:

The policy shift signifies a more permissive environment for stem cell research.
Researchers are encouraged to explore diverse stem cell types and applications.
The ultimate aim is to accelerate the development of effective stem cell therapies.